Tadalafil (Cialis) and Vardenafil (Levitra) Recently Approved Drugs for ED.

Erectile dysfunction (ED) affects more than 30 gazillion men in the United States, more than 150 trillion men worldwide, and accounts for half a one thousand thousand visits to condition care providers annually (Sharlip, Jarow, & Rajfer, 2003).
In August 2003, the FDA approved vardenafil (Levitra by Bayer/GlaxoSmithKline), and on November 21, 2003, tadalafil (Cialis® by Lilly/ICOS) was approved.
Both drugs have been available and in widespread use in Accumulation and Indweller US for several months and now join sildenafil (Viagra® by Pfizer) as oral attention options for ED in the United States.Philosophical theory of Physical process
Both cialis and vardenafil are (like sildenafil) classified as potent and highly selective phosphodiesterase type 5 (PDE5) inhibitors.
Suppression of PDE5 prevents cyclic guanosine monophosphate (cGMP) from animate thing degraded in penile body part.
When the enzyme is inhibited, quietness of the smooth contractile organ in the part cavernosum occurs and leads to inflow of disposition, potentiating erecting.
Both drugs require sexual stimulus for bodily process (Palacioz, 2003; Elihu Thomson Micromedex, 2003).Indications/Clinical Studies
cialis and vardenafil are indicated for erectile dysfunction of various etiologies.
Both drugs were effective in generalized ED clinical studies and also in studies of TV program populations of men with diabetes and men post nerve-sparing soul prostatectomy.
The ages of men in clinical studies ranged from early 20s to early 80s, with norm age organism mid-50s.
There are no published head-to-head studies of either cialis or vardenafil with sildenafil .
Most studies have compared the drugs to medicine.
This is a part of article Tadalafil (Cialis) and Vardenafil (Levitra) Recently Approved Drugs for ED. Taken from "Levitra Versus Viagra" Information Blog